Powder preparation of sugar apple (Annona squamosa L.) and analyzing its potencies as anti-gout and anti-COVID-19

Gout and COVID-19 have been of global concerns. One the drugs for gout is allopurinol that acts as a xanthin oxidase inhibitor (XOI). However, this drug has side effects, so we need safer from herbal sources such sugar apple. Sugar apple ethanol extract can act XOI, but activity steeping with hot water not known. Besides, several compounds are also reported to be active anti-viruses, their categorized against COVID-19. This study aimed at making powder apple, which was brew using water, determined phytochemical content, including TPC TFC, tested its XOI profile bond S protein The results showed contained alkaloids, flavonoids, polyphenols, TFC levels 0.048% 0.099%, XOI. Furthermore, in silico analysis shown three namely quercetin-3-glucoside, rutin, kaempferol-3-rutinoside bound RBD COVID-19, it predicted anti-COVID-19 activity.